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Harrison’s Manual of Medicine



CONTENTS

Editors
Contributors
Preface
Notice
Glossary


Section 1: Important Signs and Symptoms
Section 2: Medical Emergencies
Section 3: Disorders of The Eye, Ear, Nose, and Throat
Section 4: Dermatology
Section 5: Nutrition
Section 6: Hematology and Oncology
Section 7: Infectious Diseases
Section 8: Cardiovascular Diseases
Section 9: Respiratory Diseases
Section 10: Renal Diseases
Section 11: Gastrointestinal Diseases
Section 12: Allergy, Clinical Immunology, and Rheumatology
Section 13: Endocrinology and Metabolism
Section 14: Neurology
Section 15: Psychiatric Disorders and Psychoactive Substance Use
Section 16: Adverse Drug Reaction
Section 17: Laboratory Values




SECTION 1
IMPORTANT SIGNS AND SYMPTOMS

1. Pain and Its Management

2. Chest Pain

3. Abdominal Pain

4. Headache and Facial Pain

5. Back and Neck Pain

6. Fever, Hyperthermia, Chills, and Rash

7. Pain or Swelling of Joints

8. Syncope and Faintness

9. Dizziness and Vertigo

10. Acute Visual Loss and Double Vision

11. Paralysis and Movement Disorders

12. Aphasias and Related Disorders

13. Sleep Disorders

14. Dyspnea

15. Cough and Hemoptysis

16. Cyanosis

17. Edema

18. Nausea, Vomiting, and Indigestion

19. Weight Loss

20. Dysphagia

21. Diarrhea, Constipation, and Malabsorption

22. Gastrointestinal Bleeding

23. Jaundice and Evaluation of Liver Function

24. Ascites

25. Overt Manifestations of Renal Disease

26. Electrolytes/Acid-Base Balance

27. Anemia and Polycythemia

28. Lymphadenopathy and Splenomegaly


SECTION 2
MEDICAL EMERGENCIES

29. Cardiovascular Collapse and Sudden Death

30. Shock

31. Sepsis and Septic Shock

32. Acute Pulmonary Edema

33. Confusion, Stupor, and Coma

34. Stroke

35. Subarachnoid Hemorrhage

36. Increased Intracranial Pressure and Head Trauma

37. Hypoxic-Ischemic Encephalopathy

38. Status Epilepticus

39. Poisoning and Drug Overdose

40. Diabetic Ketoacidosis and Hyperosmolar Coma

41. Hypoglycemia

42. Infectious Disease Emergencies

43. Oncologic Emergencies

44. Drowning and Near-Drowning

45. Anaphylaxis and Transfusion Reactions

46. Bites, Venoms, Stings, and Marine Poisonings

47. Hypothermia and Frostbite


SECTION 3
DISORDERS OF THE EYE, EAR, NOSE, AND THROAT

48. Common Disorders of the Eye

49. Hearing Disorders

50. Infections of the Upper Respiratory Tract


SECTION 4
DERMATOLOGY

51. General Examination of the Skin

52. Common Skin Conditions


SECTION 5
NUTRITION

53. Assessment of Nutritional Status

54. Enteral and Parenteral Nutrition

55. Eating Disorders

56. Obesity


SECTION 6
HEMATOLOGY AND ONCOLOGY

57. Examination of Blood Smears and Bone Marrow

58. Red Blood Cell Disorders

59. Leukocytosis and Leukopenia

60. Bleeding and Thrombotic Disorders

61. Transfusion and Pheresis Therapy

62. Cancer Chemotherapy

63. Myeloid Leukemias, Myelodysplasia, and Myeloproliferative Syndrome

64. Lymphoid Malignancies

65. Skin Cancer

66. Head and Neck Cancer

67. Lung Cancer

68. Breast Cancer

69. Tumors of the Gastrointestinal Tract

70. Genitourinary Tract Cancer

71. Gynecologic Cancer

72. Prostate Hyperplasia and Carcinoma

73. Cancer of Unknown Primary Site

74. Sarcomas of Bone and Soft Tissues

75. Paraneoplastic Endocrine Syndromes

76. Neurologic Paraneoplastic Syndromes


SECTION 7
INFECTIOUS DISEASES

77. Diagnosis

78. Antimicrobial Therapy

79. Immunization and Advice to Travelers

80. Infective Endocarditis

81. Intraabdominal Infections

82. Infectious Diarrheas

83. Sexually Transmitted Diseases and Reproductive Tract Infections

84. Infections of Skin, Soft Tissues, Joints, and Bones

85. Infections in the Immunocompromised Host

86. HIV Infection and AIDS

87. Hospital-Acquired Infections

88. Pneumococcal Infections

89. Staphylococcal Infections

90. Streptococcal/Enterococcal Infections and Diphtheria

91. Meningococcal and Listerial Infections

92. Infections Caused by Haemophilus, Bordetella, Moraxella, and HACEK Group Organisms

93. Diseases Caused by Gram-Negative Enteric Bacteria, Pseudomonas, and Legionella

94. Diseases Caused by Other Gram-Negative Bacteria

95. Anaerobic Infections

96. Nocardiosis and Actinomycosis

97. Tuberculosis and Other Mycobacterial Infections

98. Lyme Disease and Other Spirochetal Infections

99. Rickettisial Infections

100. Mycoplasma Infections

101. Chlamydial Infections

102. Herpesvirus Infections

103. Cytomegalovirus and Epstein-Barr Virus Infections

104. Influenza and Other Viral Respiratory Diseases

105. Rubeola, Rubella, Mumps, and Parvovirus Infections

106. Enteroviral Infections

107. Insect- and Animal-Borne Viral Infections

108. Fungal Infections

109. Pneumocystis carinii Infection

110. Protozoal Infections

111. Helminthic Infections and Ectoparasite Infestations


SECTION 8
CARDIOVASCULAR DISEASES

112. Physical Examination of the Heart

113. Electrocardiography and Echocardiography

114. Preoperative Evaluation of Cardiovascular Disease

115. Arrhythmias

116. Congestive Heart Failure and Cor Pulmonale

117. Congenital Heart Disease in the Adult

118. Valvular Heart Disease

119. Cardiomyopathies and Myocarditis

120. Pericardial Disease

121. Acute Myocardial Infarction

122. Chronic Coronary Artery Disease and Unstable Angina

123. Prevention of Atherosclerosis

124. Hypertension

125. Disease of the Aorta

126. Peripheral Vascular Diseases


SECTION 9
RESPIRATORY DISEASES

127. Respiratory Function and Diagnosis of Pulmonary Disease

128. Asthma and Hypersensitivity Pneumonitis

129. Environmental Lung Diseases

130. Chronic Bronchitis, Emphysema, and Acute or Chronic Respiratory Failure

131. Pneumonia and Lung Abscess

132. Pulmonary Thromboembolism and Primary Pulmonary Hypertension

133. Interstitial Lung Disease (ILD)

134. Disease of the Pleura, Mediastinum, and Diaphragm

135. Disorders of Ventilation, Including Sleep Apnea

136. Pulmonary Insufficiency and Acute Respiratory Distress Syndrome (ARDS)


SECTION 10
RENAL DISEASES

137. Approach to the Patient with Renal Disease

138. Acute Renal Failure

139. Chronic Renal Failure (CRF) and Uremia

140. Dialysis

141. Renal Transplantation

142. Glomerular Disease

143. Renal Tubular Diseases

144. Urinary Tract Infections

145. Renovascular Disease

146. Nephrolithiasis

147. Urinary Tract Obstruction


SECTION 11
GASTROINTESTINAL DISEASES

148. Peptic Ulcer and Related Disorders

149. Inflammatory Bowel Diseases

150. Colonic and Anorectal Diseases

151. Cholelithiasis, Cholecystitis, and Cholangitis

152. Pancreatitis

153. Acute Hepatitis

154. Chronic Hepatitis

155. Cirrhosis and Alcoholic Liver Disease

156. Portal Hypertension


SECTION 12
ALLERGY, CLINICAL IMMUNOLOGY, AND RHEUMATOLOGY

157. Diseases of Immediate Type Hypersensitivity

158. Primary Immunodeficiency Diseases

159. SLE, RA, and Other Connective Tissue Diseases

160. Vasculitis

161. Ankylosing Spondylitis

162. Degenerative Joint Disease

163. Gout, Pseudogout, and Related Diseases

164. Psoriatic Arthritis

165. Reactive Arthritis and Reiter's Syndrome

166. Other Arthritides

167. Sarcoidosis

168. Amyloidosis


SECTION 13
ENDOCRINOLOGY AND METABOLISM

169. Disorders of the Anterior Pituitary and Hypothalamus

170. Disorders of the Posterior Pituitary

171. Disorders of the Thyroid

172. Disorders of the Adrenal Gland

173. Diabetes Mellitus

174. Disorders of the Male Reproductive System

175. Disorders of the Female Reproductive System

176. Hypercalcemic and Hypocalcemic Disorders

177. Osteoporosis and Osteomalacia

178. Disorders of Lipid Metabolism

179. Hemochromatosis, Porphyrias, and Wilson's Disease


SECTION 14
NEUROLOGY

180. The Neurologic Examination

181. Diagnostic Methods in Neurology

182. Seizures and Epilepsy

183. Tumors of the Nervous System

184. Bacterial Infections of the Central Nervous System

185. Aseptic Meningitis, Viral Encephalitis, and Prion Diseases

186. Chronic Meningitis

187. Multiple Sclerosis

188. Alzheimer's Disease and Other Dementias

189. Parkinson's Disease

190. Ataxic Disorders

191. ALS and Other Motor Neuron Diseases

192. Cranial Nerve Disorders

193. Autonomic Nervous System Disorders

194. Spinal Cord Diseases

195. Peripheral Neuropathies, Including Guillain-Barré Syndrome

196. Myasthenia Gravis

197. Muscle Diseases


SECTION 15
PSYCHIATRIC DISORDERS AND PSYCHOACTIVE SUBSTANCE USE

198. Approach to the Patient with Psychiatric Symptoms

199. Psychiatric Medications

200. Alcoholism

201. Narcotic Abuse


SECTION 16
ADVERSE DRUG REACTION

202. Adverse Drug Reactions


SECTION 17
LABORATORY VALUES

203. Laboratory Values of Clinical Importance